KEGG   REACTION: R00994
Entry
R00994                      Reaction                               
Name
(2R,3S)-3-methylmalate:NAD+ oxidoreductase
Definition
2-Oxobutanoate + CO2 + NADH + H+ <=> D-erythro-3-Methylmalate + NAD+
Equation
C00109 + C00011 + C00004 + C00080 <=> C06032 + C00003
Reaction class
RC00001  C00003_C00004
RC00417  C00109_C06032
Enzyme
1.1.1.85
Pathway
rn00290  Valine, leucine and isoleucine biosynthesis
rn00660  C5-Branched dibasic acid metabolism
rn01100  Metabolic pathways
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
Module
M00535  Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.85
     R00994  2-Oxobutanoate + CO2 + NADH + H+ <=> D-erythro-3-Methylmalate + NAD+
Orthology
K00052  3-isopropylmalate dehydrogenase [EC:1.1.1.85]
Other DBs
RHEA: 32718

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (11)   
   KEGG PATHWAY (10)   
   KEGG MODULE (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
Gene (8185)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (8184)   
All databases (8206)   

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